Osteoinductive nanofiber scaffold for bone regeneration
نویسندگان
چکیده
منابع مشابه
PLGA/nHA hybrid nanofiber scaffold as a nanocargo carrier of insulin for accelerating bone tissue regeneration
The development of tissue engineering in the field of orthopedic surgery is booming. Two fields of research in particular have emerged: approaches for tailoring the surface properties of implantable materials with osteoinductive factors as well as evaluation of the response of osteogenic cells to these fabricated implanted materials (hybrid material). In the present study, we chemically grafted...
متن کاملAdvanced Nanocomposite Scaffold for Bone Regeneration
Introduction Each year in the United States approximately 500,000 procedures that involve the use of bone substitutes are performed. To address the limitations of materials currently used in orthopaedic tissue engineering, we have developed novel nanocomposite materials that consist of a citric acid-based elastomer, poly(1,8 octanediol citrate) (POC) and bioceramic nanoparticles, βtricalcium ph...
متن کاملTitanium foam-bioactive nanofiber hybrids for bone regeneration.
We have reported previously a method to introduce bioactive nanofiber networks through self-assembly into the pores of titanium alloy foams for bone repair. In this study we evaluate the in vitro colonization by mouse pre-osteoblastic cells of these metal-peptide amphiphile hybrids containing phosphoserine residues and the RGDS epitope. The aim was to determine the effect of varying the RGDS ep...
متن کاملSurgical preparation of bone-scaffold interface is critical for bone regeneration inside tissue engineering scaffold.
The goal of this study was to investigate if the preparation of implantation site affects bone formation inside tissue engineering scaffolds. For this purpose, two different drilling techniques were used to create a hole in distal femurs of rats before the insertion of a bone scaffold: a manually driven wood drill bit and an electrically driven metal drill bit. The size and the position of the ...
متن کاملEffect of polycaprolactone scaffold permeability on bone regeneration in vivo.
Successful bone tissue engineering depends on the scaffold's ability to allow nutrient diffusion to and waste removal from the regeneration site, as well as provide an appropriate mechanical environment. Since bone is highly vascularized, scaffolds that provide greater mass transport may support increased bone regeneration. Permeability encompasses the salient features of three-dimensional poro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.01694